Professor He at Hematology Center of Cyrus Tang Medical Institute Makes Significant Progress in Intravenous Regulatory Mechanism and Tumor Research

The National Natural Science Foundation of China, major research plans of the Ministry of Science and Technology, and outstanding disciplines in Jiangsu Province have provided funds and supports. As a result, the research group led by Professor He Yulong at the Hematology Center of Cyrus Tang Medical Institute has achieved significant progress in the study on molecular regulation mechanism through vein specification and maintenance. The related research achievement headed "Angiopoietin receptor Tie2 is required for vein specification and maintenance via regulating COUP-TFII" was published online on eLIFE on December 23.

In addition, two research groups, which are led by Professor He and Professor Qin Zhihai (the Institute of Biophysics of CAS) respectively, collaborate on tumor research by using mouse models of the macrophage knockout Tie2. They have found that the signaling pathway of macrophage Tie2 plays a significant role in the regeneration of tumor vessels and tumor recurrence following chemotherapy. On December 1, their research findings were published in Cancer Research, a famous journal in oncology.